Prophylactic Anti-diarrhoea Property of Chrysobalanus icaco Fruit Methanol Extract in Swiss Mice
Diarrhoea is one of the major health issues in the developing world due to poor water and sanitation. The methanol extract of the fruit of Chrysobalanus icaco (Coco plum) was evaluated for the prophylactic anti-diarrhoeal activity against castor oil-induced diarrhoea in Swiss mice. Diarrhoea was induced in the mice experimentally by castor oil administration, and the anti-diarrhoeal activity of various doses of the fruit extract (25, 50, and 100 mg/kg) was assessed against a control group and a reference group treated with loperamide (3 mg/kg).