Dissociation constant

Potentiometric investigations of complexes formed by chromium (III) ion and amino acids have been carried out. The dissociation constants of the amino acids, the stepwise formation constants and the overall stability constants of the metal ions and amino acids complexes were determined. The dissociation constants of the amino acids determined are; alanine (10.29), arginine (12.02), asparagine (9.39), glycine (9.87), histidine (7.01), lysine (9.28), methionine (9.68), phenyalanine (9.61), proline (10.53), threonine (10.31), tryptophan (9.77), and valine (10.28).

Potentiometric Studies on the dissociation constants of amino acids were carried out. The dissociation constants of amino acids were determined using ‘ORIGIN 50’ Program, as an attempt to find an alternative way for determination of the dissociation constants of amino acids, pKa, instead of the conventional calculation methods.