The GC-MS analysis of the volatile constituents of crude honey residue (VCHR) and its in vitro antioxidant study of the crude honey residue (CHR) has been carried out. Hydrodistillation technique was employed in the extraction of the VCHR. The various candidates present in the extract of crude honey residue (ECHR) were identified using the gas chromatography-mass spectrometry (GC-MS) instrumental method of analysis. The ECHR was investigated for in vitro antioxidant study by exploring the free radical scavenging potential via the 2,2- diphenyl-1- picrylhydrazyl, DPPH technique. A total of twenty-one (21) compounds were identified from the GC-MS analysis of ECHR with humulene (10.09%), α–methyl mannofuranoside (4.77%), 4,6-di-O-methyl-α-D-galactoside (13.25%), n-hexadecanoic acid (7.33%) and 9-octadecenoic acid (5.79%) as major constituents. The antioxidant study of ECHR witnessed an increasing activity with a free radical scavenging potential range of 4.16±0.01 to 16.47±0.12 as the concentration increased. The present study has shown the GC-MS analysis of the volatile constituents and its in vitro antioxidant activity of crude honey residue from Takum Local Government Area of Taraba State, Nigeria.
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