Paracetamol is notorious for causing liver damage due to excessive generation of free radicals due to overdose ingestion. The body has an antioxidant system comprising enzymes and non-enzymes, which help to mop up free radicals generated.
A study was carried out to evaluate the changes in Superoxide dismutase (SOD) and Glutathione peroxidase activities (GPx) in Allium cepa roots exposed to crude oil. Crude oil used in this study was fractionated in water (ratio 1 to 2) to produce water-soluble fractions (WSF) and water insoluble fractions (WIF). Allium cepa was grown in soil treated with 2%, 5%, 10% or 20% of Whole Crude (WC), WIF or WSF for 14 days, while the control was with distilled water. Antioxidant enzyme activity was evaluated after treatment for 14days using standard protocols.
