HOMA-IR

Effect of Paxherbal Bitters on Glucose and Insulin Levels in Male Wistar Rats Fed a High Fructose Diet

A diet high in fructose, leads to a metabolic syndrome, characterized by elevated blood sugar and insulin levels, amongst other metabolic disorders. This study sought to investigate if supplementation with Paxherbal bitters, could counteract the high-fructose diet-induced elevation of blood sugar and insulin levels. Twenty male Wistar rats, each weighing about 200 g, were divided into four groups of 5 rats each: the control, the high-fructose diet with fructose water (HFD+FW), the HFD+FW with Atorvastatin, and the HFD+FW with Paxherbal bitters, groups.