Sub-acute

Sub-acute Toxicity Study of the Ethanolic Extract of Cramp Balls (Daldinia concentrica (Bolton) Ces. & De Not.) On Wistar Albino Rats

The study was to determine the level of toxicity of repeated administration of ethanol extract of a medicinal mushroom, Daldinia concentrica in animal model. Wistar albino rats of both sexes were sorted randomly into four groups of five rats each. Graded doses of 200, 400 and 800 mg/kg of the extract were administered orally, once daily for eight consecutive days to the rats in the respective groups, while control group received 10% tween 80 in distilled water only.