Medicinal plants

Ameliorative Effects of a Polyherbal Formulation on Hepatic Function and Pancreatic Histomorphology in Streptozotocin-Induced Diabetic Male Wistar Rats

This study evaluated the ameliorative effects of a polyherbal formulation comprising Garcinia kola, Buchholzia coriacea, and Picralima nitida on hepatic function and pancreatic histomorphology in streptozotocin (STZ)-induced diabetic male Wistar rats. Thirty-five Wistar rats were randomly divided into seven groups: normal control, diabetic control, four groups treated with the polyherbal extract (100, 150, 200, and 250 mg/kg), and a positive control treated with metformin (50 mg/kg). Diabetes was confirmed 48 hours post-STZ injection (60 mg/kg).
AuthorName(s)
Stanley Edokpiawe
Joseph Omorogiuwa Erhabor

Phytochemical Profiling and Anti-Diarrhoea Activity of a Bi-herbal Aqueous Extract of Psidium guajava and Ocimum gratissimum

Diarrhoeal diseases remain a global health challenge, with rising antimicrobial resistance driving the need for plant-based therapies. This study evaluated the phytochemical composition and anti-diarrhoeal activity of a bi-herbal aqueous extract derived from Psidium guajava and Ocimum gratissimum. The phytochemical analyses were performed using standard methods. The in vitro anti-diarrhoeal activity of the extract was assessed against selected diarrhoeagenic microorganisms (Escherichia coli, Salmonella sp., Shigella dysenteriae, and Aspergillus niger) using the agar well diffusion technique.
AuthorName(s)
Joseph Omorogiuwa Erhabor
Oghenekevwe Otobrise

Ethnomedical Survey of Medicinal Plants Sold in Local Markets in Akure South, Ondo State, Nigeria

Globally, millions of people in the developing world rely on medicinal plants to improve their primary health care, income generation and livelihood. An ethnomedicinal survey was conducted in four markets in Akure South Local Government Area of Ondo State, Nigeria. The aim was to document the diversity of medicinal herbs sold in the markets, their modes of preparation, the plant part(s) used, dosage, and the method of utilization. The respondents were primarily women, consisting of buyers and sellers of the herbals.

AuthorName(s)
J.O. Erhabor
O. Timothy

Assessment of Prolonged Administration of SynriamTM on Haematological Parameters and Lipid Profiles of Rats

University of Ilorin, Faculty of Life Sciences, Department of Biochemistry, Ilorin, Nigeria

Antibacterial effect of leaf extract of Ricinus communis

The antibacterial activity of aqueous, ethanolic and methanolic extracts of Ricinus communis were studied by the agar diffusion method. The ethanolic extract produced the greatest antimicrobial activity and the aqueous extract the least. Staphylococcus aureus was the most sensitive to the extracts while Bacteroides fragilis was the most resistant. The minimum bactericidal concentration of the extracts ranged between 60% (w/v) and 100% (w/v). Thus the extracts of Ricinus communis could be useful as a source of antibiotics against aerobic and anaerobic bacteria.

AuthorName(s)
A. Banso
A. Sani

Antibacterial effect of leaf extract of Ricinus communis

The antibacterial activity of aqueous, ethanolic and methanolic extracts of Ricinus communis were studied by the agar diffusion method. The ethanolic extract produced the greatest antimicrobial activity and the aqueous extract the least. Staphylococcus aureus was the most sensitive to the extracts while Bacteroides fragilis was the most resistant. The minimum bactericidal concentration of the extracts ranged between 60% (w/v) and 100% (w/v). Thus the extracts of Ricinus communis could be useful as a source of antibiotics against aerobic and anaerobic bacteria.

AuthorName(s)
A. Banso
A. Sani
Subscribe to Medicinal plants