Gastro-Protective Activity of Methanol Leaf Extract of Polyalthia longifolia (Sonn.) Thw. on Ethanol-Induced Ulceration in Rats
The study evaluates the gastro-protective activity of methanol extract of the leaves of Polyalthia longifolia (Sonn.) Thw. in Wistar rats. Single daily dose of the extract (200, 400 and 800 mg/kg body weight) were administered orally to the respective groups of experimental rats for 28-consecutive days. The control and standard groups received distilled water and ranitidine (10 ml/kg and 250 mg/kg body weight) respectively. At the end of the period, they were exposed to a single oral dose of 75% ethanol.