O. O. Famakinwa

In vitro cytotoxic effect of aqueous and hydroethanolic leaf extracts of Stachytarpheta cayennensis on the human pancreatic cell line (ASPC-1)

There is an urgent need for agents with improved efficacy against pancreatic cancer, as only 20% of pancreatic cancer patients undergoing chemotherapy respond to treatment. This study investigated the antiproliferative attributes of hydroethanolic and aqueous leaf extracts of Stachytarpheta cayennensis on human pancreatic carcinoma cell lines (AsPC-1). Human pancreatic (AsPC-1) cells were seeded (1.07×105 cells/well) into 96 well microtitre plate, allowed to stabilize, then exposed for 24hrs to graded (0 – 10000 μg ml-1)