Rat

Evaluating Psidium guajava (Guava) Leaf Extracts Ability to Improve Biochemical and Haematological Indices in Anaemic Rats

Psidium guajava (Guava) leaf is used to cure a variety of illnesses, including cough, gastrointestinal pain, gastroenteritis, diarrhea and inflammatory conditions. This study aimed to determine the effect of aqueous extract of Psidium guajava leaf on biochemical and haematological parameters on phenylhydrazine-induced rat. Twenty-Five male Wistar rats, aged between 8 – 10 weeks, were divided into five groups of five rats per group.
AuthorName(s)
Chinedu-Ndukwe
Akpbabio, J.S
Chukwuemeka, B.C
P.A, Amadi
Amadi A.N.C.

Hypoglycemic, Hematologic and Hypolipidemic Potential of Hippophae rhamnoides (Berry Oil) in Alloxan-induced Diabetic Rats

This study was carried out to evaluate the hypoglycemic, hematologic and hypolipidemic potential of berry oil in alloxan-induced adult Wistar rat. Five groups of Wistar rats (4 rats per group) Group 1 served as “Normal control” rats and received normal rat pellets and water. Diabetes mellitus was induced in Groups 2, 3, 4, and 5 by intraperitoneal injection of alloxan (160 mg/kg). Group 3 rats were treated with glibenclamide (5 mg/kg body weight), groups 4 and 5 received 500 mg/kg and 1000 mg/kg body weight of Berry oil daily respectively for 21 days via oral gavage.

AuthorName(s)
Chinedu-Ndukwe, P. A.*
Amadi A.N.C.
Onuoha, M. C.
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