Histopathological Evidence of the Protective Effect of Arachis hypogea Seed on 1,2-Dimethylhydrazine-Dihydrochloride-Induced Liver Damage in Rats
This study examined the effect of peanut-supplemented diet on the serum antioxidant status and
histomorphological changes induced by 1,2-dimethylhydrazine-dihydrochloride on rat liver. Twenty-eight healthy albino
Wistar rats used for this study were divided into seven groups of 4 rats each. The toxicant, 1,2-dimethylhydrazinedihydrochloride (DMH), was administered subcutaneously at a dose of 25 mg/kg body weight. Group A (control) rats were
maintained on normal rat feed. The Group B and C rats were maintained on normal feed, administered DMH for 12 and 24
weeks respectively.