Cardio-Pulmonary Biosafety of “Makann” a Bi-Herbal Formulation
The study aimed to evaluate the biosafety of “Makann”, an aqueous bi-herbal formulation of the root extract of Garcinia kola and Carica papaya (BH) on the heart and lungs of adult female albino mice. Garcinia kola and Carica papaya roots were harvested, prepared into a bi-herbal extract (BH), and administered to the test group while the control group received distilled water. Mice were divided into 3 test groups and 3 control groups of 5 animals: single dose 24 h test groups, single-dose 14-day test group, and daily dose 14-day test group.