Letrozole Ameliorates Dexamethasone-Induced Cardiometabolic Risk in Wister Rats
Dexamethasone is a glucocorticoid, often prescribed for various inflammatory and immunological disorders. However, its role in promoting cardiometabolic risk has been widely reported. This study investigated the ameliorative effects of letrozole on dexamethasone-induced cardiometabolic disorder in rats. Twenty male Wister rats were randomly divided into control, letrozole (1 mg/kg, p.o), dexamethasone (0.2 mg/kg, p.o) and dexamethasone + letrozole groups.