Evaluation of the Modulatory Effect of Aqueous Extract of Dialium guineense Stem Bark on Oxidative Status of Diabetic Rats Liver
Oxidative stress is implicated in the pathogenesis of diseases, such that drugs with strong antioxidant property are promoted for health management. The present study evaluated the modulatory effect of aqueous extract of Dialium guineense (AEDG) stem bark on oxidative status of diabetic rat liver. Adult male rats (Wistar strain, n = 20, mean weight = 165 ± 15 g) were randomly assigned to four groups (5 rats/group): control, diabetic, metformin, and extract groups. Diabetes mellitus (DM) was induced in the rats via intraperitoneal injection of streptozotocin (STZ, 50 mg/kg body weight, bwt).