Hormones

Pregnancy and Fetal Outcomes Following Metformin Use in Diabetic Rats

The female reproductive system is responsible for pregnancy and supports development of the fetus. The incidence of diabetes mellitus (DM) is increasing rapidly worldwide (Wild et al., 2000). Metformin is an oral antidiabetic drug and it seems to have properties that could be beneficial in managing reproductive complications of DM. The present study determined the effect of metformin on pregnancy and fetal outcomes in Alloxan-induced diabetic female Sprague-Dawley rats. Eighty (80) pregnant rats were divided into four groups (20 rats per group).

Oligospermic Effects of Aqueous Extract of Fragaria ananassa (Strawberry) On Male Wistar Rats

Fragaria ananassa (strawberry fruit) is a popularly consumed fruit that is well known to contain potent antioxidants. The effects of aqueous extract of Fragaria ananassa on the sperm parameters and hormones were investigated in male adult Wistar rats. Fifteen (15) male Wistar rats were used for this experiment and were randomly assigned into a control group (A) and two treatment group (B and C) with each group containing five animals (n=5 per group).

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