A.F. Afolabi

Sub-acute Exposure to Sodium Selenite-induced Dyslipidemia, ATPase-independent Electrolytes Disruption and Tissue Damage in Male Wistar Rats

Selenium (Se) is a trace element required for many cellular functions in most organisms although also known to be toxic, has a narrow range separating chronic conditions of deficiency and toxicity. This study investigated the effects of exposure to different doses of Se as sodium selenite on some biochemical markers in male albino rats. Twenty-four rats grouped into four with six animals each were used. One of the groups served as control given distilled water and the other three groups were respectively given 16, 32, and 64 ppm Se orally in their drinking water for 4 weeks.