Anti-fertility

Anti-fertility and Pro-fertility Activities of Desplatsia dewevrei (De Wild. & Th. Dur.) Burret on Wistar Rats

Desplatsia dewevrei (De Wild. & Th. Dur.) Burret fruits were investigated for possible anti-fertility and profertility activities by hematological, biochemical and hormonal assays using Wistar rats of both sexes for 6 weeks. Methanol extract of Desplatsia dewevrei fruits was administered orally at 50 and 100 mg/kg. Results show that concentrations above 50 mg/kg interfered with the reproductive development of the liter (fetus) in female rats. While in male rats, doses above 50 mg/kg posed adverse effect on sperm count and sperm motility.