Curcumin

Curcumin and Quercetin Ameliorates Reserpine-Induced Neurotoxicity in Drosophila melanogaster Models

Reserpine has reportedly been used to induce neurotoxicity in animal models, including Drosophila melanogaster, and has been reported to cause oxidative stress, mitochondrial dysfunction, and neuroinflammation, while Curcumin and quercetin have demonstrated anti-inflammatory and antioxidant properties.
AuthorName(s)
Lola Adeola Adelakin
Olufunto Omodele Adeleye
Ayodeji David Adeoye
Bayo Olufunso Adeoye
Afoluwajuwonlo Gamaliel Obaoye1
Joseph Igbo Enya
Nyangrimam Musa
John Afees Olanrewaju

Modulatory Effects of Curcumin on Antioxidant Status of Benzo[a]pyrene Treated Albino Rats

This study examined the modulatory effects of Curcumin on the antioxidant status of benzo[a]pyrene-treated albino rats. Thirty albino rats were divided into five treatment groups (n=6) namely: control, benzo[a]pyrene only (1 mg/kg), benzo[a]pyrene (1 mg/kg) + Curcumin (50 mg/kg), benzo[a]pyrene (1 mg/kg) + Curcumin (100 mg/kg), Benzo[a]pyrene (1 mg/kg) + Curcumin (200 mg/kg) for 6 weeks. Rats were administered the drug (benzo[a]pyrene and Curcumin) orally, thrice a week.

AuthorName(s)
Kolade, O.Y.*
Oladiji, T.A
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