Quantitative Analysis of γ-Globin Gene Expression in Human Erythroleukaemic K562 Cells Treated with Theobroma cacao Bark Ethanolic Extract
Therapeutic reactivation of foetal haemoglobin (HbF) can alleviate clinical complications associated with
sickle cell anaemia (SCA), a severe monogenic disorder that is prevalent in sub-Saharan Africa. Traditional medicine
practitioners in Nigeria utilize the stem bark of Theobroma cacao as a haematinic for SCA patients, but its potential to
induce HbF remains uncertain.