Hematology

Analysis of Hematological Indices and Serum Immunoglobulin Levels (IgG and IgM) in Preeclamptic and Normotensive Pregnancies

 Preeclampsia (PE) is a common complication during pregnancy, affecting 2–5% of pregnant women. It is believed to be associated with modulaton of immune response. This study investigated some hematological indices and serum levels of immunoglobulins- Ig G and IgM in pre-eclamptic and normotensive patients attending Ante-natal Clinic at the University of Benin Teaching Hospital Benin City, Nigeria.

Anti-fertility and Pro-fertility Activities of Desplatsia dewevrei (De Wild. & Th. Dur.) Burret on Wistar Rats

Desplatsia dewevrei (De Wild. & Th. Dur.) Burret fruits were investigated for possible anti-fertility and profertility activities by hematological, biochemical and hormonal assays using Wistar rats of both sexes for 6 weeks. Methanol extract of Desplatsia dewevrei fruits was administered orally at 50 and 100 mg/kg. Results show that concentrations above 50 mg/kg interfered with the reproductive development of the liter (fetus) in female rats. While in male rats, doses above 50 mg/kg posed adverse effect on sperm count and sperm motility.