N.U. Asiriuwa

Assessment of Some Kidney Function Indices and Kidney Histopathology of Wistar Rats Exposed to Crude Palm Oil of Varied Free Fatty Acid Levels

Palm oil is a major source of dietary fats and oils in many regions of the world. In this study, the effect of crude palm oil (CPO) of varied free fatty acid (FFA) levels on some kidney function indices and kidney histopathology in Wistar rats was investigated. Thirty-six female Wistar rats were grouped into six categories: a control group with no palm oil intake and five experimental groups receiving crude palm oil with FFA levels of 0.4 %, 4.8 %, 8.4 %, 21.9 % and 42.7 %, respectively. The rats were administered a dosage of 480 mg/kg body weight of CPO for four weeks.