Antileishmaniasis, phytotoxicity and cytotoxicity of Nigerian Euphorbiaceous Plants 2: Phyllanthus amarus and Phyllanthus muellerianus Extracts.
Methanolic extracts of the leaves of Phyllanthus amarus and stem of Phyllanthus muellerianus were studied for antileishmaniasis activity, phytotoxicity and cytotoxicity. The antileishmanial activity was evaluated in vitro using promastigote culture of Pakistani leishmanial strain (L. major) in 96 well micro titer plate bioassay, while phytotoxicity was assessed using the Lemna bioassay and cytotoxicity using brine shrimp lethality assay. Methanolic extract of stem of P.