Phytochemicals

Cytogenotoxicity Investigation on Three Commonly Sold Antimalarial Herbal Recipes in Southwest Nigeria Using Root Mitosis Allium cepa and Mouse Bone Marrow Micronucleus Assays

Malaria remains a major public health concern in Nigeria and some other African countries due to the high cost of its treatment with synthetic/orthodox medicines that are even resisted by Plasmodium species. Therefore, a significant number of people are using antimalarial herbal medicines that have not been toxicologically confirmed to be safe for the prevention and treatment of malaria.

Phytochemical Screening and GCMS Profile of Bioactive Natural Products in Ethanolic Root Extract of Uvaria ovate

Phytochemical and gas chromatography and mass spectrometry (GCMS) analysis of the ethanolic extract of Uvaria ovata (Uo) roots was carried out. Phytochemical analysis showed high amounts of alkaloids, tannins and flavonoids, moderate amounts of saponins, terpenes and cardiac glycosides, while steroids and phenols were found in little quantities. Gas chromatography and mass spectrometry analysis revealed the presence of eleven compounds, of which D-Streptamine and Cystine were prominent.