Rats

The use of plant extracts to treat diseases in herbal medicine has the potential of causing toxic effects, though of natural origin, it may not be safe. This study evaluated the effect of aqueous and methanolic extract of Annona muricata stem bark consumption in normal rats. Fresh stem bark of Annona muricata (Sour soup) was collected, pulverized, extracted with distilled water or methanol (Aqueous or Methanolic extract). The rats were divided into six (6) groups of five (5) rats per group, for aqueous or methanolic extract.

Obesity is a medical condition characterised by accumulation of excess body fat which may lead to reduced life expectancy and/or increased health problems. The aim of this study was to investigate the ameliorative potential of Cyathula prostrata ethanolic leaf extract (CPLE) on olanzapine-induced obesity in rats. The Rats were randomly distributed into 6 groups, group 1 served as the control and were administered distilled water, groups 5-6 were administered 8 mg/kg bw of olanzapine for 28 days to induce obesity.

This study investigated and compared the glycaemic rises following administration of various honey samples in rats. Five Nigerian honeys [Abakaliki honey (ABH), Calabar honey (CAH), Ezzamgbo honey (EZH), Lokoja honey (LOH), Okitipupa honey (OKH)] and one Malaysian honey (MAH) were administered to non-diabetic and alloxan-induced diabetic rats. Fasting blood glucose (FBG) concentrations were measured at 0, 30, 60 and 120 min. Glucose parameters including peak blood glucose, area under curve, percentage variation in blood glucose (BG) and percentage change in BG were estimated.

This study investigated and compared the glycaemic rises following administration of various honey samples in rats. Five Nigerian honeys [Abakaliki honey (ABH), Calabar honey (CAH), Ezzamgbo honey (EZH), Lokoja honey (LOH), Okitipupa honey (OKH)] and one Malaysian honey (MAH) were administered to non-diabetic and alloxan-induced diabetic rats. Fasting blood glucose (FBG) concentrations were measured at 0, 30, 60 and 120 min. Glucose parameters including peak blood glucose, area under curve, percentage variation in blood glucose (BG) and percentage change in BG were estimated.