RT-qPCR

Quantitative Analysis of γ-Globin Gene Expression in Human Erythroleukaemic K562 Cells Treated with Theobroma cacao Bark Ethanolic Extract

Therapeutic reactivation of foetal haemoglobin (HbF) can alleviate clinical complications associated with sickle cell anaemia (SCA), a severe monogenic disorder that is prevalent in sub-Saharan Africa. Traditional medicine practitioners in Nigeria utilize the stem bark of Theobroma cacao as a haematinic for SCA patients, but its potential to induce HbF remains uncertain.