J.O. Akolade

Ameliorative Effects of Cyathula prostrata Leaf Extract on Olanzapine-Induced Obesity in Rats

Obesity is a medical condition characterised by accumulation of excess body fat which may lead to reduced life expectancy and/or increased health problems. The aim of this study was to investigate the ameliorative potential of Cyathula prostrata ethanolic leaf extract (CPLE) on olanzapine-induced obesity in rats. The Rats were randomly distributed into 6 groups, group 1 served as the control and were administered distilled water, groups 5-6 were administered 8 mg/kg bw of olanzapine for 28 days to induce obesity.