Acute Toxicity Studies and In Vitro Effects of Guiera senegalensis (Sabara) Leaf Aqueous Extract on Trypanosoma brucei
Trypanosomes are a type of protozoan that is spread by the bite of an infected tsetse fly and causes nagana in animals and African trypanosomiasis (also known as sleeping sickness) in people. The purpose of this study was to identify the phytochemical components and acute lethal dose of Guiera senegalensis and to study the effects of its leaf aqueous extract on Trypanosoma brucei. Standard analysis methods were used in this study. Aside the acute toxicity (LD50) test, both the phytochemical and the anti-trypanosomal potential of Guiera senegalensis were carried out in-vitro.