Ameliorative Effects of Methanol Leaf Extract of Justicia carnea on Streptozotocin-Induced Diabetic Organopathy in Wistar Rats: A Histopathological Assessment
Diabetes mellitus is a chronic metabolic disorder marked by persistent hyperglycemia, which progressively impairs multiple organ systems. This study evaluated the histopathological effects of streptozotocin (STZ)-induced diabetes on the pancreas, liver, and kidneys of Wistar rats, and also assessed the protective potential of the methanol leaf extract of Justicia carnea. Thirty-six male Wistar rats were assigned to six groups (n = 6). Group 1 served as the normal control, while diabetes was induced in the remaining groups with STZ (50 mg/kg).