Nephropathy

Investigation of the Modulatory Effect of Aqueous Extract of Dialium guineense Stem Bark on Oxidative Status of Diabetic Rat Kidneys

Streptozotocin (STZ) is a chemical compound known to damage pancreatic β-cells and cause hyperglycemia. Hyperglycemia plays a key role in glomerular, mesangial cell, and tubular damage in kidneys. Metabolic dysregulation, including hyperglycemia, initiates cellular damage in the kidneys. The present study investigated the modulatory effect of aqueous extract of Dialium guineense (AEDG) stem bark on oxidative status of diabetic rat kidneys.
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