Arachis hypogaea Seeds Reduced Glucose Metabolism in Colon of Rats Exposed to 1,2-Dimethylhydrazine
The aim of this study was to ascertain the effects of peanut diet supplementation on glucose metabolism in rats exposed to 1, 2-dimethylhydrazine. Lactate dehydrogenase and glucose -6-phosphate dehydrogenase activities were used as indices for glucose metabolism. Eighty-four rats of both sexes were used for this study and were divided into seven groups of 6 rats each. 1, 2- dimethylhydrazine (DMH) was administered subcutaneously at a dose of 25 mg/kg body weight.Group A rats were maintained on rat feed, group B rats were maintained on rat feed and administered DMH once weekly for 12 weeks.