Effect of a Dual-Formula of Picralima nitida and Cymbopogon citratus Extract on Expression of APC and P53 Genes in Benzene-Induced Haematotoxicity in Wistar Rats
The leaves of Picralima nitida and Cymbopogon citratus are potential therapeutic agents; studies have explored their role in modulating gene expression. Therefore, this study aims to determine the effect of a dual formula of Picralima nitida and Cymbopogon citratus extracts on p53 and APC genes in benzene-induced haematotoxicity in Wistar rats. The study involved 60 male Wistar rats, divided into six groups, to evaluate the effect of a Picralima nitida and Cymbopogon citratus leaf extract blend on p53 and APC mRNA levels.