Vol. 17, No. 2

Heavy metals levels in dried Clarias gariepinus and Channa obscura from three major markets in Benin metropolis were investigated in this work. Samples were purchased, dried and digested by standard method and the metals levels were determined using Atomic Absorption Spectrophotometer (AAS). The mean levels of cadmium and lead (0.48±0.06 and 1.36±1.13 mg/kg) and (0.62±0.45 and 5.60±7.43 mg/kg) for Clarias gariepinus and Channa obscura were found to be higher than EU standard.

Sustainable use of soil on which agriculture depends is absolutely necessary for agricultural productivity. Soil samples were collected from two auto-mechanic workshops sited at Technical College Road (Station A) and Textile Mill Road (Station B) while the control was at EDPA Housing Estate, all in Benin City with the aid of a split soil core sampler at a depth of 0  10cm. The Physicochemical parameters of the samples were analysed using standard methods and revealed pH mean value of 7.27 at station A and 6.83 at station B respectively.

Sustainable use of soil on which agriculture depends is absolutely necessary for agricultural productivity. Soil samples were collected from two auto-mechanic workshops sited at Technical College Road (Station A) and Textile Mill Road (Station B) while the control was at EDPA Housing Estate, all in Benin City with the aid of a split soil core sampler at a depth of 0  10cm. The Physicochemical parameters of the samples were analysed using standard methods and revealed pH mean value of 7.27 at station A and 6.83 at station B respectively.

 Cisplatin is a very effective chemotherapeutic agent used in treating various types of cancer, but its application may have damaging effects on testicular morphology. In this study, the effect of vitamin C, a known antioxidant, on cisplatin-induced testicular damage was investigated. Thirty Wistar rats were grouped into six groups (A-F) of five rats per group.

Cisplatin is a very effective chemotherapeutic agent used in treating various types of cancer, but its application may have damaging effects on testicular morphology. In this study, the effect of vitamin C, a known antioxidant, on cisplatin-induced testicular damage was investigated. Thirty Wistar rats were grouped into six groups (A-F) of five rats per group. Cisplatin was given as a single dose of 8 mg/kg body weight 24 hours prior to daily vitamin C administration at l00 mg and 200 mg respectively, for two weeks in 2 ml distilled water by gastric gavage.

There is an urgent need for agents with improved efficacy against pancreatic cancer, as only 20% of pancreatic cancer patients undergoing chemotherapy respond to treatment. This study investigated the antiproliferative attributes of hydroethanolic and aqueous leaf extracts of Stachytarpheta cayennensis on human pancreatic carcinoma cell lines (AsPC-1).

There is an urgent need for agents with improved efficacy against pancreatic cancer, as only 20% of pancreatic cancer patients undergoing chemotherapy respond to treatment. This study investigated the antiproliferative attributes of hydroethanolic and aqueous leaf extracts of Stachytarpheta cayennensis on human pancreatic carcinoma cell lines (AsPC-1). Human pancreatic (AsPC-1) cells were seeded (1.07×105 cells/well) into 96 well microtitre plate, allowed to stabilize, then exposed for 24hrs to graded (0 – 10000 μg ml-1) 

Senna alata and Senna podocarpa are medicinal plants widely used in complementary and alternative medicine in the treatment of various diseases, in southwestern Nigeria. The in vitro cytotoxic and genotoxic potential of a formulation composed of methanolic leaf extract of S. alata (75%) and S. podocarpa (25%), on Human Epithelial Squamous Carcinoma (HEp-2) cells was investigated.

Senna alata and Senna podocarpa are medicinal plants widely used in complementary and alternative medicine in the treatment of various diseases, in southwestern Nigeria. The in vitro cytotoxic and genotoxic potential of a formulation composed of methanolic leaf extract of S. alata (75%) and S. podocarpa (25%), on Human Epithelial Squamous Carcinoma (HEp-2) cells was investigated.

 The use of antibiotics in animal husbandry has helped in the reduction of animal diseases. However, health workers as well as enlightened consumers are becoming more concerned with the health implications such as resistance associated with the use of antibiotics since the same group of antibiotics are used in human medicine.Sixty (60) samples from pork meat, piggery environment and abbatoir effluent were screened for the presence of bacteria by selective and differential cultural procedures. Susceptibility of isolates to antibiotics and plasmid