Volume 17, No 1 , 2016

Modulatory Effects of Curcumin on Antioxidant Status of Benzo[a]pyrene Treated Albino Rats

This study examined the modulatory effects of Curcumin on the antioxidant status of benzo[a]pyrene-treated albino rats. Thirty albino rats were divided into five treatment groups (n=6) namely: control, benzo[a]pyrene only (1 mg/kg), benzo[a]pyrene (1 mg/kg) + Curcumin (50 mg/kg), benzo[a]pyrene (1 mg/kg) + Curcumin (100 mg/kg), Benzo[a]pyrene (1 mg/kg) + Curcumin (200 mg/kg) for 6 weeks. Rats were administered the drug (benzo[a]pyrene and Curcumin) orally, thrice a week.

Characterisation of Hydrocarbon Pollutants in Soils from Selected Areas in Abraka, Delta State, Nigeria

The concentration, distribution and sources of petroleum hydrocarbons in soils from selected areas in Abraka, Delta State, were evaluated. Soil samples were collected from areas suspected to be contaminated with petroleum hydrocarbons, which were also in proximity to human population. These areas included busy junctions, generator maintenance workshops, suya joint, drainage and fuel stations. Samples were extracted using nhexane/dichloromethane mixture and quantified using gas chromatograph-flame ionization detector.

Evaluating the Concept of Reducing Sugar (Glucose) and Growth in L-Asparaginase Production Using Some Selected Marine Actinomycetes

: Reducing sugar is a sugar that serves as a reducing agent. It falls under the category of carbohydrate or natural sugar but it consist of either a free aldehyde group (-CHO) or a ketone groups called the reducing end of the sugar. Microbial growth describes an increase in cell number of microorganisms provided with suitable nutritional and environmental conditions. This study evaluated the concept of reducing sugar and growth in L- asparaginase production using some selected marine actinomycetes.

Possible Potency of Annona muricata L. Methanol Leaf Extract in Ameliorating Pancreatic Cell Function in Alloxan-induced Diabetic Mice

The methanol extract of Annona muricata leaf was investigated for its effects on -cell dysfunction, and atherogenenic dyslipidaemia in alloxan-induced diabetic mice. Thirty (30) mice of both sexes, aged between 8-10 weeks were randomly divided into normal, diabetic, diabetic + glibenclamide(5mg/kg), diabetic+250 mg/kg A. muricata Extract, diabetic+500 mg/kg A. muricata Extract, diabetic+1000 mg/kg A. muricata Extract, groups (n=6/group). Alloxan was administered intraperitoneally while extracts and glibenclamide were given via oral route for 21 days. The results revealed that, 250 mg/kg A.

Antibacterial Activity of Alcohol-Based Hand Sanitizers on Some Clinical Bacterial Isolates

This study was carried out to investigate the antibacterial activities of commercially available alcohol-based handsanitizers (2Sure, Dettol and Carex) on some clinical bacterial isolates. The isolates were obtained from the laboratory stock culture of University of Benin Teaching Hospital, Benin City.

Molecular Characterization of Iron-Related Bacteria in Ground Water in Yenagoa, Bayelsa State, Nigeria

Fe (III) compounds which are formed from the oxidation of Fe(II) by iron bacteria precipitates, and forms iron oxides - an extensive orange mats of organic material, which is often found present in the ground water, evident by the rust stain colour seen on almost all the water storage tanks in Yenagoa, Bayelsa State, Nigeria. Hence, this study characterized iron bacteria diversity in groundwater, which is a major source of drinking water in the state.

Effect of Soil Types and Mechanical Scarification on the Germination and Seedling Growth of Cola nitida Schott & Endl.

The major problem in Cola propagation is related to seed germination and slow growth rate, hence this study was designed to ascertain the effect of soil types and mechanical scarification on the germination and seedling growth of Cola nitida. The experiment was a two factored experiment of 4 soil type (Topsoil, topsoil combined with carbonized sawdust (TSCSD), topsoil combined with river soil (TSRS) and River soil) and 2 scarification (Nicked and Whole seed) laid in a Completely Randomized Design (CRD) with 3 replicates.

Effect of Ethyl Methanesulfonate (EMS) on the Germination, Growth and Yield of Two Okra (Abelmoschus esculentus (L.) Moench) Varieties

The study was conducted to investigate the effect of different concentrations of ethyl methanesulfonate (EMS) on the growth and yield of two okra (Abelmoschus esculentus L. Moench) varieties (V35 and Clemson spineless). The experiment was conducted in the screen house and field at Michael Okpara University of Agriculture, Umudike, Abia State. The screen house experiment was set up in a complete randomized design (CRD) with three replications. The field trial was set up in randomized complete block design (RCBD) with three replications.

Preliminary Study on the Effect of Different Concentrations of EMS on Two Pigeon Pea (Cajanus cajan L. Millsp.) Accessions

In the present study, seeds of Pigeon pea (Cajanus cajan L. Millspaugh) accessions (Brown and Cream colours) were treated with different concentrations of Ethyl methane sulphonate (0.0 %, 0.01 %, 0.02 %, 0.03 %, 0.04 %, 0.05 %, 0.06 % and 0.07 %). The seeds were sown and monitored for 30 days. Data obtained showed a trendy effect. Data obtained showed that germination percentage was decreased with an increase in the mutagen concentration when compared with the control.

Impact of a Digital Health Platform (NimCure) on Adherence Enhancement in Tuberculosis Therapy

The study was a 2-arm individually randomized clinical trial conducted at the Nigeria Institute of Medical Research (NIMR) in Lagos, Nigeria, aimed to improve the overall patient adherence to tuberculosis treatment using Video Observed Therapy (VOT). A total of 100 participants were recruited to this study. Data was collected through the NimCure mobile app and patient records. Results obtained showed a high rate of at least 90% adherence to TB treatment was achieved in both VOT and DOT groups.