The methanol extract of Annona muricata leaf was investigated for its effects on blood glucose, haematology, serum electrolyte and kidney parameters of alloxan-induced diabetic mice. Six groups of mice (5 mice per group) was used for this study. Group A served as “Normal control” and fed mice pellets and water. Diabetes was induced in Groups B, C, D, and E by intraperitoneal injection of alloxan (90 mg/kg).
The methanol extract of Annona muricata leaf was investigated for its effects on -cell dysfunction, and atherogenenic dyslipidaemia in alloxan-induced diabetic mice. Thirty (30) mice of both sexes, aged between 8-10 weeks were randomly divided into normal, diabetic, diabetic + glibenclamide(5mg/kg), diabetic+250 mg/kg A. muricata Extract, diabetic+500 mg/kg A. muricata Extract, diabetic+1000 mg/kg A. muricata Extract, groups (n=6/group). Alloxan was administered intraperitoneally while extracts and glibenclamide were given via oral route for 21 days. The results revealed that, 250 mg/kg A.
This study was carried out to investigate the antibacterial activities of commercially available alcohol-based handsanitizers (2Sure, Dettol and Carex) on some clinical bacterial isolates. The isolates were obtained from the laboratory stock culture of University of Benin Teaching Hospital, Benin City.
Herbs are increasingly used across the globe; In fact, the World Health Organization reported that most African countries, including Nigeria, depend on herbal medicines for primary health care, without much documented evidence of adverse effects. Agbo polyhebral extract is popular in Nigeria, especially among (but not limited to) the local populace of the southwestern areas. The aim of this study is to determine the effects of malaria alcoholic herbal extract (Agbo) on renal, liver, oxidative stress markers and hematological parameters on wistar rats.
Fe (III) compounds which are formed from the oxidation of Fe(II) by iron bacteria precipitates, and forms iron oxides - an extensive orange mats of organic material, which is often found present in the ground water, evident by the rust stain colour seen on almost all the water storage tanks in Yenagoa, Bayelsa State, Nigeria. Hence, this study characterized iron bacteria diversity in groundwater, which is a major source of drinking water in the state.
The antibacterial activity of aqueous, ethanolic and methanolic extracts of Ricinus communis were studied by the agar diffusion method. The ethanolic extract produced the greatest antimicrobial activity and the aqueous extract the least. Staphylococcus aureus was the most sensitive to the extracts while Bacteroides fragilis was the most resistant. The minimum bactericidal concentration of the extracts ranged between 60% (w/v) and 100% (w/v). Thus the extracts of Ricinus communis could be useful as a source of antibiotics against aerobic and anaerobic bacteria.
Investigations based on field records and experiences at the Guinea Fowl Production Research Unit of the Kainji Lake Research Institute have shown that some diseases management conditions which include: yolksac, fungal infections, collibacillosis, helminthiasis, management problems in particular inbreeding, moulting, heatstroke and nutritional deficiencies affect significantly the reproductive organs, egg laying and hatchability.
Drinking water sources are epidemiologically suspected as one of the major transmission agents for pathogenic and perhaps drug resistant Enterobacteria. Accordingly, in the period October, 1995 – September, 1996, water samples as were available from tap, borehole, well, dams and rivers in randomly selected 19 Local Government areas of Kano State were screened for these bacteria. 1201 isolates comprising Citrobacter sp. (16.91%); Enterobacter aerogenes (14.99%); Klebsiella sp. (10.24%); Proteus sp. (9.58%); Shigella sp. (9.49%); Escherichia coli (8.24%); Salmonellae (7.99%) and Vibrio sp.
Mosquito coils (bars), formulated from three plant leaves, namely; Acalypha torta, Carica papaya and Calotropis gigantica, and seeds of Peganum harmala, were tested as repellents or toxicants against laboratory reared Culex sp. adult mosquitoes when burnt as an incense. None of the plants showed toxic activity, as knockdown was less than 5% in all cases. Slight repellency was observed with Acalypha sp. (0.21) and P. harmala (0.19), as these showed significant difference (P < 0.05) from values recorded for the control, i.e. bars without plant material.
Susceptibility responses of cat fish – Clarias gariepinus to infection with Pseudomonas aeruginosa vis-à-vis treatment with chloramphenicol were investigated in the present study. Thirty healthy and physically active fishes weighing between 200-350g sourced from Challawa Gorge Dam, Karaye, Kano State were used for the study. These were divided into three aquarium tanks A, B, C (ten in each case). Fishes in A were infected with 1.0ml (about 1.2 x 106 cfu/ml) of Pseudomonas aeruginosa pyrenterally through linea alba by ventral medial furrow. This was
