Evaluation of the Antimicrobial, Antioxidant and the Staining Property of Cnestis ferruginea Ethanoic Fruit Extract

 Plants contain variety of bioactive compounds known to have chemotherapeutic value some of these plants also have dyes. Against the background, this study is aimed at determining the nutritional composition, antimicrobial, antioxidant and staining properties of Cnestis ferrugenea fruit. Plant fruits were collected and processed using soxhlet extraction technique. Phytochemical analysis was determined using standard laboratory method. Phenolic content estimation of plant fruits was determined using folin-ciocalteu (F.C) method. Antioxidant was estimated using 2,2 diphenyl-1-picrylhydrazyl (DPPH) . Cnetis ferrugenea fruit extract had anti-fungi activity but low antibacterial activity. Phytochemical analysis of plant fruit shows the presence of alkaloid, saponin, tannin, flavonoid and cardiac- glysoside. Nutritional compositions are total ash, moisture, crude fibre, lipid, carbohydrate and protein. MIC of fruit extract is 6.25 and has IC50 value 15966.02 with pH of 4.6. Cnetis ferruginea ethanoic fruit extract stained fungal isolates but didn’t stain bacteria isolate. Studied fruit extract is a good source of carbohydrate, crude fibre and moisture content, it has antioxidant, antifungal and staining properties but low antibacterial properties. Free radicals are central cause of disease, knowledge of antimicrobial and antioxidant properties of plants extract will help pharmaceutical company formulate products that will combat the menace of free radicals. Some medicinal plants possess natural dyes.

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255-261
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Discovery of Eriodictyol as Putative Exportin-1 Inhibitor for Non-small Cell Lung Cancer Therapy

Department of Biochemistry, Faculty of Life Sciences, University of Ilorin, Ilorin, Nigeria