Dexamethasone is a glucocorticoid, often prescribed for various inflammatory and immunological disorders. However, its role in promoting cardiometabolic risk has been widely reported. This study investigated the ameliorative effects of letrozole on dexamethasone-induced cardiometabolic disorder in rats. Twenty male Wister rats were randomly divided into control, letrozole (1 mg/kg, p.o), dexamethasone (0.2 mg/kg, p.o) and dexamethasone + letrozole groups.

Phyllanthus amarus is a highly medicinal plant with its therapeutic activities spanning a wide scope of diseases and ailments. Earlier literatures indicated the effectiveness of this plant in combating hepatitis, malaria, diabetes, and cancer. In the present study the effect of ethanol extract of P. amarus on colon cancer in Swiss albino mice induced by 1, 2 dimethylhydrazine (DMH) was investigated. 15 female Swiss mice of weight 25-35g were acclimatized for a week and randomized into 3 groups (5 per group). Group A (-DMH), Group B (DMH, 300mg/kg body weight of ethanol extract of P.

Proximate composition, percentage daily value and anti- nutritional levels of raw and boiled leaves of Heinsia crinata (HC) and Vernonia amygdalina (VA) were investigated using standard methods. There was no significant difference (p > 0.05) between the crude protein values of VA (3.80%) and HC (3.76%). Boiling decreased the protein content of the vegetables (HC: 3.65±0.02%; VA: 3.70±0.02%). The ash content of HC (2.36±0.02%) was significantly higher (p < 0.05) than the ash content of VA (1.64±0.02%) but boiling decreased their ash content.

The aim of this study was to examine the epidemiology of intestinal parasites and determine the risk factors linked to infection among primary school children in the Amai community. The research was conducted with 778 students from May to November 2017. Stool samples were obtained and tested for intestinal parasites using the direct smear (wet mount) technique, demographic and epidemiological information were obtained using well-structured questionnaires and the statistical analysis was carried out using Microsoft Excel and GraphPad Prism.

Microplastic pollution poses a growing threat to aquatic ecosystems and biodiversity due to its persistence and potential harm to human health. This study examines the occurrence, distribution, and ecological impact of microplastics in surface water from River Nun, Bayelsa Central, Nigeria. Sampling was conducted at six locations over six months (January–March and July–September 2024). Samples were processed using NOAA techniques, including filtration, density separation, and microscopy, while FTIR and GC-MS were used for polymer and additive analysis.

The accumulation of metals in different environmental compartments poses a risk to both the environment, human and biota health. The combination of both Phyto and nano remediation techniques have been gaining more attention in this regard. This technique leverage on the unique and specific absorption qualities of plant roots, and employs these inherent processes with the bioaccumulation, translocation, and pollutant degrading capacities of the whole plant as well as cost effectiveness, and potential to treat a broad range of contaminants.

Industrial processes, including scrap yards, can contaminate surface waters with heavy metals, posing a risk to aquatic habitat and human health. Thus, the concentrations, ecological and health risks of heavy metals in surface water and sediment of the Ogun River in Lagos was investigated. Surface water and sediments collected from the Ogun River were analyzed for some physicochemical parameters and heavy metals using standard procedures.

The aim of this study is to assess heavy metals levels, pollution indices and ecological risks of floodplain sediments in urban areas in Delta State, Nigeria. The levels of nine heavy metals (Cd, Pb, Cr, Ni, Cu, Co, Mn, Zn and Fe) were measured in floodplain sediments of urban areas in Delta State, Nigeria. Sediment samples from the nine urban areas were collected for three months (July-September) covering the wet season. The sediment samples were digested with aqua regia, and the heavy metal levels in the digests were quantified by means of atomic absorption spectrometry.

This study aimed to evaluate the risks associated with water quality in public institutions in Warri, Delta State. Water samples were collected from five public institutions namely, School, Hospital, Mall, Church and Hotel. Physico-chemical and microbial analyses were conducted using standard methods. The water quality index (WQI) and risk assessment matrix (RAM) were applied the quality and potential risks. Results revealed slightly acidic pH levels (5.1-6.63) in water samples. Dissolved oxygen levels (3.8-4.2 mg/L) were below WHO recommendations.