Alkaloid, Flavonoid, Fatty Acid and Vitamin Profiles of the Unripe Fruit of Solanum melongena L. (Round Variety)

 Solanum melongena L. (round variety) is an eggplant that is commonly called “garden egg” in Nigeria. The unripe fruit is often eaten as snack, dessert or vegetable. The dried fruit powder was evaluated for its alkaloid, flavonoid and fatty acid profiles by Gas Chromatography (GC). The vitamin profile was estimated by High Performance Liquid Chromatography (HPLC). The alkaloid profile showed the presence of high amounts of solamargine (134 ± 0.719 mg/100g) and solasonine (115 ± 0.455 mg/100g), with other alkaloids present in lower 

Characterization of antibiogram susceptibility profile of Vibrio species isolated from fresh vegetables

Fresh vegetables water leaf (Talinum traingnlare), pumpkin leaf (Telfairia occidentalis) and scent leaf (Ocinum gratissimum) collected from urban markets in Benin City, Nigeria, were investigated for the presence of Vibrio species using standard microbiological techniques. The antibiotic susceptibility profiles of the isolates against a panel of 13 antibiotics, was carried out according to the method described by The National Committee for Clinical Laboratory Standards (NCCCLS).

Antibiotic Resistance and Plasmid Profile of Bacterial Isolates from Pork Meat Retailed in Benin City

 The use of antibiotics in animal husbandry has helped in the reduction of animal diseases. However, health workers as well as enlightened consumers are becoming more concerned with the health implications such as resistance associated with the use of antibiotics since the same group of antibiotics are used in human medicine.Sixty (60) samples from pork meat, piggery environment and abbatoir effluent were screened for the presence of bacteria by selective and differential cultural procedures. Susceptibility of isolates to antibiotics and plasmid 

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Physiological Response of Human Epithelial Squamous Carcinoma (HEp-2) cells to a Di-Herbal Formulation

Senna alata and Senna podocarpa are medicinal plants widely used in complementary and alternative medicine in the treatment of various diseases, in southwestern Nigeria. The in vitro cytotoxic and genotoxic potential of a formulation composed of methanolic leaf extract of S. alata (75%) and S. podocarpa (25%), on Human Epithelial Squamous Carcinoma (HEp-2) cells was investigated.

Histopathological Evaluation of the Effects of Vitamin C on Cisplatin-induced testicular damage in Wistar albino Rats

 Cisplatin is a very effective chemotherapeutic agent used in treating various types of cancer, but its application may have damaging effects on testicular morphology. In this study, the effect of vitamin C, a known antioxidant, on cisplatin-induced testicular damage was investigated. Thirty Wistar rats were grouped into six groups (A-F) of five rats per group.

Physicochemical analysis of automobile waste oil on soil quality in Benin City, Nigeria

Sustainable use of soil on which agriculture depends is absolutely necessary for agricultural productivity. Soil samples were collected from two auto-mechanic workshops sited at Technical College Road (Station A) and Textile Mill Road (Station B) while the control was at EDPA Housing Estate, all in Benin City with the aid of a split soil core sampler at a depth of 0  10cm. The Physicochemical parameters of the samples were analysed using standard methods and revealed pH mean value of 7.27 at station A and 6.83 at station B respectively.

Heavy Metals Levels in Dried Fish Consumed in Benin and Warri Metropolis; Levels and Health Risk Assessment

Heavy metals levels in dried Clarias gariepinus and Channa obscura from three major markets in Benin metropolis were investigated in this work. Samples were purchased, dried and digested by standard method and the metals levels were determined using Atomic Absorption Spectrophotometer (AAS). The mean levels of cadmium and lead (0.48±0.06 and 1.36±1.13 mg/kg) and (0.62±0.45 and 5.60±7.43 mg/kg) for Clarias gariepinus and Channa obscura were found to be higher than EU standard.

Bioconcentration and Translocation Factors of Heavy Metals in Rhizophora racemosa and Sediments from Egbokodo Mangrove Swamp, Delta State, Nigeria

The mangrove ecosystem is well known to be impacted by anthropogenic activities such as oil spillage, agricultural run-off, industrial effluents, and mining in coastal areas. These activities increase heavy metals accumulated by mangroves, which are eventually released back into the environment via decomposition. This study aimed to analyze the concentration of heavy metals including cadmium (Cd), Zinc (Zn), lead (Pb), and copper (Cu) in the roots and leaves of Rhizophora racemosa and mangrove sediments obtained from Egbokodo mangrove swamp in Delta State, Nigeria.

Biomarkers of Female Infertility: Exposure, Effect and Chemical Modification of Biomolecules

Female infertility is a health condition that affects the ability of woman to conceive over a period of continuous sexual intercourse. This condition has led to psychological and social anguish, anxiety, and depression resulting from hormonal impairment, disease infection, oxidative stress, xenobiotics, environmental pollutants, and other factors. Need to say, extensive studies on the biomarkers for female infertility are still in the developmental stage in reproductive medicine to unravel remedies based on improved technologies.

Development of Congenic Mutants and Genetic Analysis of Virulence in Cryptococcus Neoformans

Cryptococcus neoformans strains were isolated from clinical source taken from the University of Benin Teaching Hospital (UBTH) and environmental source taken from New Benin Market. Two strains were selected; clinical isolate 4832 and environmental isolate NBM5. They were determined to be of two different mating types, due to differences in their susceptibility to the antifungal agent fluconazole. In order to check the involvement of mating type locus in the virulence of C. neoformans, congenic mutants were developed.