Diabetes mellitus

Helicobacter pylori is a Gram-negative microaerophilic bacteria with a spiral (helical) morphology which is usually found in the stomach. H. pylori infection is one of the most common bacterial infection worldwide and in children of lower ages. Reports show that this bacterium is associated with simple dyspepsia, heartburn and peptic ulcer diseases, most commonly leading to upper gastrointestinal bleeding and ultimately to the severe compilation of gastric malignancy. Diabetes mellitus is an important factor that increases the susceptibility and risk of various infections in the host.

Prostate disorders are age-related issues that are known to be influenced by sex hormones, diet, and lifestyle and stress. With increasing dissatisfaction with orthodox treatment methods, host of alternative therapies including medicinal plants are currently being employed. The present study investigated the effect of oral administration of aqueous extract of Momordica charantia leaf tea on prostate gland health.

The female reproductive system is responsible for pregnancy and supports development of the fetus. The incidence of diabetes mellitus (DM) is increasing rapidly worldwide (Wild et al., 2000). Metformin is an oral antidiabetic drug and it seems to have properties that could be beneficial in managing reproductive complications of DM. The present study determined the effect of metformin on pregnancy and fetal outcomes in Alloxan-induced diabetic female Sprague-Dawley rats. Eighty (80) pregnant rats were divided into four groups (20 rats per group).

The methanol extract of Annona muricata leaf was investigated for its effects on -cell dysfunction, and atherogenenic dyslipidaemia in alloxan-induced diabetic mice. Thirty (30) mice of both sexes, aged between 8-10 weeks were randomly divided into normal, diabetic, diabetic + glibenclamide(5mg/kg), diabetic+250 mg/kg A. muricata Extract, diabetic+500 mg/kg A. muricata Extract, diabetic+1000 mg/kg A. muricata Extract, groups (n=6/group). Alloxan was administered intraperitoneally while extracts and glibenclamide were given via oral route for 21 days. The results revealed that, 250 mg/kg A.

The methanol extract of Annona muricata leaf was investigated for its effects on -cell dysfunction, and  atherogenenic dyslipidaemia in alloxan-induced diabetic mice. Thirty (30) mice of both sexes, aged between 8-10 weeks were randomly divided into normal, diabetic, diabetic + glibenclamide(5mg/kg), diabetic+250 mg/kg A. muricata Extract, diabetic+500 mg/kg A. muricata Extract, diabetic+1000 mg/kg A. muricata Extract, groups (n=6/group). Alloxan was administered intraperitoneally while extracts and glibenclamide were given via oral route for 21 days.

The methanol extract of Annona muricata leaf was investigated for its effects on blood glucose, haematology, serum electrolyte and kidney parameters of alloxan-induced diabetic mice. Six groups of mice (5 mice per group) was used for this study. Group A served as “Normal control” and fed mice pellets and water. Diabetes was induced in Groups B, C, D, and E by intraperitoneal injection of alloxan (90 mg/kg).

The methanol extract of Annona muricata leaf was investigated for its effects on -cell dysfunction, and atherogenenic dyslipidaemia in alloxan-induced diabetic mice. Thirty (30) mice of both sexes, aged between 8-10 weeks were randomly divided into normal, diabetic, diabetic + glibenclamide(5mg/kg), diabetic+250 mg/kg A. muricata Extract, diabetic+500 mg/kg A. muricata Extract, diabetic+1000 mg/kg A. muricata Extract, groups (n=6/group). Alloxan was administered intraperitoneally while extracts and glibenclamide were given via oral route for 21 days. The results revealed that, 250 mg/kg A.