Volume 24 , Issue 4,December 2023

Effects of Aqueous Leaf Extract of Cymbopogon citratus on Cement Dust-Induced Interstitial Pneumonitis in Adult Wistar Rats

Inhalation of cement dust is the most important cause of respiratory diseases among people with cement dust related occupations such as cement factory and transporting workers, construction labourers, brick masons, concrete finishers, plasterers, steel erectors et cetera. This study aimed to investigate the effects of aqueous leaf extract of Cymbopogon citratus on cement dust-induced lung damage in the adult Wistar rats. Thirty (30) adult Wistar rats weighing between 240 g and 270 g were divided into five (5) groups of six (6) rats per group.

Effects of Allium cepa on Lipid Profile and Cardiac Enzyme Marker in Wistar Rats Fed with High-Fat Diet

Allium cepa has been reported to contain some phytochemicals that have possible effects on weight reduction and circulating lipids. This experiment is aimed at observing the effect of A. cepa on the lipid profile and cardiac enzyme marker of albino Wistar rats fed with high-fat diet. Exactly 48 Wistar rats were used in this experiment, and were separated into four different groups as A, B, C and D. Each group had 12rats. The groups were given feed with different compositions as: normal rat feed; A. cepa supplemented rat feed; high-fat diet and A.

Various parts of Moringa oleifera ameliorate Phenylhydrazine-Induced Spleen toxicity in Male Wistar Rats

The toxicity of sickle cell anaemia maintenance drugs makes medicinal plants viable alternatives. The protective roles of Moringa oleifera (MO) parts (Bark, flower, leaf, root and seed) against phenylhydrazine (PHZ) induced spleen toxicity and oxidative stress in rats were carried out. Splenomegaly was observed in anaemic rats and was reversed by M. oleifera parts, particularly the flower and roots. The M.

Taxonomic Significance of Leaf Epidermal Attributes of some Herbaceous Species of Euphorbia L. (Euphorbiaceae) in Nigeria

Foliar epidermis of six species of Euphorbia Linn. in Nigeria was studied with the aim of ascertaining reliable characters for easy identification, delimitation and indicating relationships among species. Light microscopy was employed to evaluate leaf surface features such as shape of epidermal cell, stomata and trichome and their distribution frequency. Epidermal shapes are variable i.e. polygonal, irregular and undulate. Stomatal complex types include anomocytic, anisocytic, paracytic, diacytic were encountered. Diacytic stomatal complex was observed only in E. heterophylla and E.

Histological Changes in the Heart and Aorta of the Adult Wistar Rat Following Exposure to Cement Dust

The heart is a vital organ of the body that pumps blood through the aorta and its branches which provide blood flow to all organs and tissues of the body. Any injury causes distortion of the smooth functioning of the cardiovascular system. This study investigated the histological changes in the heart and aorta of Wistar rats following exposure to cement dust. Twenty-four (24) Wistar rats weighing between 250 g and 280 g were divided into 4 groups of 6 rats per group.

Comparative Effect of Coconut Oil and Milk on the Testis and Weight of Male Albino Rats as it Relates to Fertility

The comparative effects of coconut oil (Cocos nucifera) and coconut milk on the testis using male rats as model was studied. A total of 40 rats weighing between 200-240 g were used in the study. Group 1 served as the control and received distilled water only. Groups 2-4 were the test groups and were fed with the coconut extracts orally for 4 weeks. Group 2 was fed with coconut oil; group 3 was fed with coconut milk while group 4 was fed with the mixture of coconut oil and coconut milk respectively.

Hepato-Protective and Curative Activities of Leaf Extracts of Andrographis paniculata in Carbon Tetrachloride Induced Damage in Experimental Male Rats

The liver is a vital organ in the body that performs many functions. Many of these functions generate free radicals, which degenerate to loss of liver function. The antioxidants in the body neutralize the effect of the free radicals generated. The body is healthy when the antioxidants adequately neutralize free radicals. Carbon tetrachloride is usually used to model experimental liver damage in animals. This research investigated the possible protective and curative effect of the aqueous and ethanol extracts of Andrographis paniculata leaf on CCl4-induced liver damage in male rats.

Organochlorine Pesticides in Soils of Municipal Solid Waste Dumpsites in Delta State: Spatial and Seasonal Variations, Potential Risks and Sources

This study assessed the spatial and seasonal variations, potential risks and sources of organochlorine pesticides in municipal solid waste dumpsites (MSWDs) in Delta State. Soil samples were obtained from twenty-seven MSWDs in Delta State. Soil samples were extracted with hexane/dichloromethane and cleaned up in a column of silica gel and florisil. The OCPs in the extracts were quantified with a gas chromatograph-mass spectrometry (GC-MS). The ∑20 OCPs levels in the soils varied between 0.74 and 7.29 ng g-1for the dry season and from 0.09 to 9.47 ng g-1 for the wet season.

Compositional Pattern and Human Exposure Risk of Polycyclic Aromatic Hydrocarbons (PAHs) in Fine Dust from Indoor Environments in Port Harcourt, Nigeria

Indoor fine dusts in residential buildings, public buildings and vehicles from Port Harcourt, Nigeria were assessed for their polycyclic aromatic hydrocarbons (PAHs) concentrations, compositional patterns, and human exposure risks. The PAHs in the dust samples were quantified by gas chromatograph equipped with mass spectrometry (GC-MS) after extraction by ultra-sonication with hexane/dichloromethane/acetone and cleaned up on a silica gel/alumina column.

Antidyslipidemic Potential of Aqueous Extract of Petiveria Alliaceae Leaf on Fructose-Induced Metabolic Syndrome in Rats

This study investigated the antidyslipidemic activities of the aqueous extract of Petiveria alliaceae leaves against high fructose-induced metabolic syndrome in male wistar rats. Forty-five male Wistar rats were randomized into two groups of control (n =15) and high fructose diet (n = 30) , each group received water and control diet and fructose enriched diet and water ad- libitum respectively for six weeks to induce metabolic syndrome.